人民卫生出版社系列期刊
ISSN 2096-2738 CN 11-9370/R

中国科技核心期刊(中国科技论文统计源期刊)
2020《中国学术期刊影响因子年报》统计源期刊

新发传染病电子杂志 ›› 2017, Vol. 2 ›› Issue (1): 22-24.

• 论著 • 上一篇    下一篇

痰涂阳和涂阴肺结核的危险因素、症状及其并发症的比较研究

郭建琼1, 严晓峰2, 杨松2   

  1. 1.第三军医大学第一附属医院感染科,重庆 400038;
    2.重庆市公共卫生医疗救治中心结核五科,重庆 400036
  • 收稿日期:2016-12-07 出版日期:2017-02-28 发布日期:2020-07-01
  • 通讯作者: 杨松,Email:ir596yangsongq@aliyun.com

Comparative study on the risk factors,symptoms and complications between sputum smear positive pulmonary tuberculosis and sputum smear negative pulmonary tuberculosis

GUO Jian-qiong1, YAN Xiao-feng2, YANG Song2   

  1. 1. Department of Infectious Disease,Third Military Medical University,Chongqing 4000038,China;
    2. Department of Tuberculosis,Chongqing Infectious Disease Medical Center,Chongqing 400036,China
  • Received:2016-12-07 Online:2017-02-28 Published:2020-07-01

摘要: 目的 比较痰涂阳和涂阴肺结核的危险因素、症状及并发症的差异,为诊断、预后判断及传染源控制措施的制定提供科学依据。方法 采用非匹配病例对照法,选择2014年1月至2015年12月期间的活动性痰涂阳和涂阴肺结核住院患者126例,其中痰涂阳肺结核患者76例,痰涂阴肺结核患者50例。通过单因素分析,对比两组患者间的肺空洞、低蛋白血症、肺结核复治病史、咳痰发生率、并发肺炎和贫血的差异性,计算两组间的χ2值、OR值及95%CI,RR值及95%CI,明确痰涂阳和涂阴肺结核潜在危险因素、症状及并发症等方面的差异。结果 痰涂阳和涂阴肺结核两组患者性别及职业分布无统计学差异。单因素分析显示,肺空洞、低蛋白血症、肺结核复治病史是涂阳肺结核的独立危险因素。痰涂阳肺结核与涂阴肺结核两组咳痰的发生率、并发肺炎和贫血具有统计学意义。结论 痰涂阳肺结核发病的危险因素是肺部空洞、低蛋白血症和肺结核复治病史。痰涂阳肺结核患者的咳痰、肺炎和贫血的发生率显著高于涂阴肺结核。加强复治、低蛋白血症及肺部空洞的涂阳肺结核患者的痰液管理,早期抗结核治疗,积极防治肺炎和贫血,对于控制痰涂阳肺结核的传播、流行和治愈率的提高具有重要意义。

关键词: 痰涂阳肺结核, 痰涂阴肺结核, 危险因素, 症状, 并发症

Abstract: Objective To compare the differences on the risk factors,symptoms and complications between sputum smear positive pulmonary tuberculosis and sputum smear negative pulmonary tuberculosis,so as to provide the scientific evidences for diagnosis,prognosis and the control of infectious sources. Methods A non matching case-control method,selection of activities during the period of January 2014 to December 2015 of sputum smear positive and smear negative pulmonary tuberculosis patients in 126 cases,76 patients were diagnosed as sputum smear positive pulmonary tuberculosis and 50 cases were smear negative pulmonary tuberculosis. All cases data were collected. χ2 values,odds raitios(OR),relative risk(RR) and 95% confidence interval were calculated respectively. The differences among the risk factors,symptoms and prognosis between the patients with smear positive pulmonary tuberculosis and smear negative pulmonary tuberculosis were analyzed by statistical method. Results There is no significant difference in the distributions of sex and occupation between the two groups. The single variable analysis showed that pulmonary cavities,hypoproteinem-ia,history with retreated pulmonary tuberculosis were independent risk factors being associated with smear positive pulmonary tuberculosis. The prevalence of expectoration,complication of pneumonia and anemia between the two groups had significant differences. Conclusions The risk factors of sputum smear positive pulmonary tuberculosis were pulmonary cavities,hypoproteinemia and history with retreated pulmonary tuberculosis. The incidence of expectoration,pneumonia or anemia of patients with sputum smear positive pulmonary tuberculosis were significantly higher than the cases with sputum smear negative pulmonary tuberculosis. Therefore,the sputum management of smear positive pulmonary tuberculosis with retreated pulmonary tuberculosis history,pulmonary cavities is important,and positiveprevention and early treatment of pneumonia or anemia will play a very crucial role in the diseases control and improvement of cure rate.

Key words: Sputum smear positive pulmonary tuberculosis, Sputum smear negative pulmonary tuberculosis, Risk factor, Symptom, Prognosis