冠状病毒起源、受体及新型冠状病毒检测与疫苗最新研究进展

新发传染病电子杂志 ›› 2020, Vol. 5 ›› Issue (2): 74-78.

冠状病毒起源、受体及新型冠状病毒检测与疫苗最新研究进展

郝鹏飞¹, 许汪¹, 杜寿文², 金宁一¹, 吴诗品², 李昌¹, 李体远²

1.军事科学院军事医学研究院军事兽医研究所,中国医学科学院人兽共患病毒病防控关键技术研究创新单元,长春 130062;
2.暨南大学第二临床医学院,深圳市人民医院感染内科,广东深圳 518020

收稿日期:2020-04-06 出版日期:2020-02-20 发布日期:2020-06-19
通讯作者: 李体远,Email：tiyuan_li@163.com
基金资助:
1、长春市科技局应急攻关项目（2020RW002）；
2、深圳市政府卫生“三名工程”专项基金（SZSM201612034）

Coronavirus origin, receptor and recent advances in novel coronavirus detection and vaccine

Hao Pengfei¹, Xu Wang¹, Du Shouwen², Jin Ningyi¹, Wu Shipin², Li Chang¹, Li Tiyuan²

1. Research Unit of Key Technologies for Prevention and Control of Virus Zoonoses, Chinese Academy of Medical Sciences, Military Veterinary Institute, Academy of Military Medical Sciences, Changchun 130122, China;
2. Department of Infectious Diseases, the Second Clinical Hospital of Jinan University, Shenzhen People's Hospital, Guangdong Shenzhen 518020, China

Received:2020-04-06 Online:2020-02-20 Published:2020-06-19

摘要/Abstract

摘要： 冠状病毒由来已久,1936年就分离到病毒并命名。冠状病毒种类很多,感染谱也比较广,一些病毒具有人兽共患特性,严重威胁人类与动物健康以及公共卫生安全,特别是2003年严重急性呼吸综合征病毒（severe acute respiratory syndrome coronavirus,SARS-CoV）、2012年中东呼吸综合征冠状病毒（Middle East respiratory syndrome coronavirus,MERS-CoV）,以及现在流行的新型冠状病毒,使得冠状病毒“名声大噪”。本文简要综述了冠状病毒的发现、起源、病毒受体以及我们在新型冠状病毒检测方法和疫苗研究方面的最新进展,以期人们更好的认识和理解冠状病毒,为新型冠状病毒及其他冠状病毒防控提供参考。

关键词: 冠状病毒, 起源, 受体, 检测, 疫苗

Abstract: Coronavirus has a long history. It was isolated and named in 1936. There are many types of coronavirus, and the infection spectrum is relatively wild. Some viruses have the characteristics of zoonosis, which seriously threaten human and animal health and public health safety. Especially, SARS virus in 2003, MERS virus in 2012, and the coronavirus in 2019. In this paper, the discovery of origin and receptor of coronavirus, as well as the latest progress in the detection methods and vaccine research of new coronavirus are briefly reviewed in order to better understand coronavirus and provide a reference for the prevention and control of new coronavirus and other coronaviruses.

Key words: Coronavirus, Origin, Receptor, Detection, Vaccine

郝鹏飞, 许汪, 杜寿文, 金宁一, 吴诗品, 李昌, 李体远. 冠状病毒起源、受体及新型冠状病毒检测与疫苗最新研究进展[J]. 新发传染病电子杂志, 2020, 5(2): 74-78.

Hao Pengfei, Xu Wang, Du Shouwen, Jin Ningyi, Wu Shipin, Li Chang, Li Tiyuan. Coronavirus origin, receptor and recent advances in novel coronavirus detection and vaccine[J]. Electronic Journal of Emerging Infectious Diseases, 2020, 5(2): 74-78.

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