人民卫生出版社系列期刊
ISSN 2096-2738 CN 11-9370/R

中国科技核心期刊(中国科技论文统计源期刊)
2020《中国学术期刊影响因子年报》统计源期刊

新发传染病电子杂志 ›› 2019, Vol. 4 ›› Issue (1): 28-32.

• 论著 • 上一篇    下一篇

162例颅内结核MRI表现与临床转归相关性分析

王召钦, 王玉香, 唐怡敏, 谭洁, 张培泽, 邓国防   

  1. 广东医科大学附属深圳市第三人民医院,广东 深圳 518112
  • 出版日期:2019-03-30 发布日期:2020-07-21
  • 通讯作者: 邓国防, Email:jxxk1035@yeah.net

Correlation between MRI imaging findings and clinical outcomes of 162 cases with intracranial tuberculosis

WANG Zhao-qing, WANG Yu-xiang, TANG Yi-min, TAN Jie, ZHANG Pei-ze, DENG Guo-fang   

  1. Department of pulmonary medicine, Shenzhen Third People's Hospital, the Affiliated hospital of Guangdong Medical College,Guangdong Shenzhen 518112,China
  • Online:2019-03-30 Published:2020-07-21

摘要: 目的 分析颅内结核患者MRI表现和治疗预后情况,探讨MRI表现与临床转归的相关性。方法 收集2011年08月至2016年12月在深圳市第三人民医院住院的确诊和临床诊断为颅内结核患者162例,将其住院时的MRI表现和其临床转归进行回顾性对比分析。结果 影像学表现为脑膜结核67例,临床治愈56例,临床治愈率为83.6%;脑实质结核52例,临床治愈37例,临床治愈率为71.2%;混合型颅内结核43例,临床治愈28例,临床治愈率为65.1%,三组比较差异无统计学意义(χ2=5.231,P=0.073)。影像学表现为脑梗死17例,临床治愈率58.8%(10/17);脑积水18例,临床治愈率50.0%(9/18);脑梗死+脑积水4例,临床治愈率75.0%(3/4),三组比较差异无统计学意义(χ2=0.888,P=0.726)。影像学表现无并发症者123例,临床治愈率80.5%(99/123);有并发症者39例,临床治愈率56.4%(22/39),两组比较差异有统计学意义(χ2=9.081,P=0.003)。结论 颅内结核影像学表现并发症者与临床治愈率有相关性,对病情转归评估可提供一定的临床参考。

关键词: 结核, 脑膜, 磁共振成像, 电子断层扫描, 转归

Abstract: Objective To analyze the correlation between MRI imaging findings and clinical outcomes in patients with intracranial tuberculosis.Methods 162 cases of intracranial tuberculosis diagnosed in the Third People's Hospital of Shenzhen from August 2011 to December 2016 were reviewed. Their MRI findings and clinical outcomes were analyzed retrospectively.Result The imaging findings and clinical outcomes were as below: 67 cases of meningeal tuberculosis, the clinical cure rate was 83.6% (56/67); 52 cases of brain parenchymal tuberculosis, the clinical cure rate was 71.2% (37/52); 43 cases of mixed intracranial tuberculosis, the clinical cure rate was 65.1%. (28/43), the difference between the three groups was not statistically significant (χ2=5.231, P=0.073). The imaging findings of complication were as below: 17 cases of cerebral infarction, the clinical cure rate was 58.8% (10/17); 18 cases of hydrocephalus, clinical cure rate was 50.0% (9/18); 4 cases of cerebral infarction and hydrocephalus, clinical cure rate was 75.0 %(3/4). The difference between the three groups was not statistically significant (χ2=0.888, P=0.726). There were 123 cases of imaging without complications, the clinical cure rate was 80.5% (99/123) and 39 cases had complications, the clinical cure rate was 56.4% (22/39). The difference between the two groups was statistically significant (χ2=9.081), P=0.003).Conclusion The imaging complications of intracranial tuberculosis were significantly correlated with clinical cure rate, this finding may provide a certain reference value for the evaluation of clinical outcomes.

Key words: Tuberculosis, Meninges, Magnetic resonance imaging (MRI), Electronic tomography, Prognosis