人民卫生出版社系列期刊
ISSN 2096-2738 CN 11-9370/R

中国科技核心期刊(中国科技论文统计源期刊)
2020《中国学术期刊影响因子年报》统计源期刊

新发传染病电子杂志 ›› 2019, Vol. 4 ›› Issue (4): 196-199.

• 卫生健康事业发展70年巡礼--重大传染病防治 • 上一篇    下一篇

重要真菌病的临床诊治与防治策略

廖万清1, 2, 陈敏1, 2   

  1. 1.上海长征医院皮肤科, 上海 200003;
    2.上海市医学真菌分子生物学重点实验室, 上海 200003
  • 出版日期:2019-12-30 发布日期:2020-07-21
  • 通讯作者: 廖万清, Email: liaowanqing@sohu.com

Clinical diagnosis and prevention strategies of important mycosis

LIAO Wan-qing1, 2, CHEN Min1, 2   

  1. 1. Department of Dermatology, Shanghai Changzheng Hospital, Shanghai 200003, Shanghai 200003, China;
    2. Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Institute of Mycology, Shanghai 200003, China
  • Online:2019-12-30 Published:2020-07-21

摘要: 真菌是与细菌、病毒并列的人类三大致病微生物之一, 主要感染免疫抑制人群。新中国成立以来我国医疗技术水平取得了很大进步, 重要真菌病的预防及临床诊治工作也取得了一大批具有国际水平的成果, 显著提高了人民群众的健康水平。但是我们也应该清醒地认识到, 随着医疗水平的提高, 使得HIV感染者、肿瘤放化疗后患者等免疫抑制人群存活率增高, 加之全球交流及气候变化, 导致高毒力、多药耐药病原真菌菌株如“超级真菌”-耳道念珠菌感染在我国多个城市散发并得到证实。因此, 未来我国重要真菌病的预防及诊治之路仍任重道远, 亟需加强临床各学科与医学真菌学、流行病学等基础学科及相关企业的协同合作, 突出流行病学、致病机制及转化研究, 加强产学研用合作, 争取早日建成具有中国特色的重要真菌病预防与诊治关键技术体系, 为世界提供具有我国特色的真菌病临床诊治标准, 为提高我国重要真菌病预防与诊治水平贡献力量。

关键词: 真菌病, 预防, 诊断, 治疗, 策略

Abstract: Parallel with bacteria and viruses, fungi are one of the three major pathogenic microorganisms in humans, which primarily infect immune-suppressed hosts. Since the founding of New China, great progress has been made in China's medical technology. A large number of internationally-level achievements have also been achieved in the prevention and clinical diagnosis and treatment of fungal diseases in China, which significantly improved the health of Chinese people. But we should be soberly aware that the improvement of medical level also brings a large number of long-term survival hosts in China, such as HIV-infected patients, patients after tumor radiotherapy and chemotherapy, etc. Moreover, high-virulence, multidrug-resistant pathogenic fungal isolates such as Candida auris (“super fungi”)- infections that caused by global exchanges and climate change have also been reported in many cities in China. Therefore, the future of prevention and treatment of important fungal diseases in China is still a long way to go. There is an urgent need to strengthen the collaboration between clinical disciplines and basic disciplines such as medical mycology and epidemiology and related companies. Particularly the epidemiology, pathogenesis, transformation of mycosis, and cooperation in production, education and research should be strengthen, striving to build a key technical system for the prevention, diagnosis and treatment of important fungal diseases at an early stage, and providing the world with clinical diagnostic criteria for mycosis with Chinese characteristics, which will significantly contribute to the prevention and treatment of important fungal diseases in China.

Key words: Mycoses, Precaution, Diagnosis, Treatment, Strategy