人类免疫缺陷病毒相关隐球菌免疫重建炎症综合征研究进展

新发传染病电子杂志 ›› 2020, Vol. 5 ›› Issue (2): 126-130.

人类免疫缺陷病毒相关隐球菌免疫重建炎症综合征研究进展

胡志亮^{1, 2}, 许传军³

1.南京中医药大学附属南京医院,南京市第二医院感染科,南京 210003;
2.南京医科大学公共卫生学院全球健康中心,南京,211166;
3.南京中医药大学附属南京医院,南京市第二医院放射科,南京 210003

收稿日期:2019-09-16 出版日期:2020-02-20 发布日期:2020-06-19
通讯作者: 胡志亮,Email：huzhiliangseu@163.com
基金资助:
1.江苏省“十三五科教强卫工程”青年医学重点人才项目（QNRC2016059）；
2.南京市医学科技发展项目（ZKX17040）

Human immunodeficiency virus-associated cryptococcal immune reconstitution inflammatory syndrome

Hu Zhiliang^{1, 2}, Xu Chuanjun³

1.Department of Infectious Disease, the Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing 210003, China;
2. Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China;
3.Department of Radiology, the Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing 210003, China

Received:2019-09-16 Online:2020-02-20 Published:2020-06-19

摘要/Abstract

摘要： 人类免疫缺陷病毒相关隐球菌免疫重建炎症综合征表现为启动抗逆转录病毒治疗后出现的原有临床隐球菌病加重或新发出现临床隐球菌病相关表现。本文就隐球菌免疫重建炎症综合征的临床特征、发病机制以及处置进行综述。

关键词: 人类免疫缺陷病毒, 艾滋病, 隐球菌, 免疫重建炎症综合征

Abstract: Cryptococcal immune reconstitution inflammatory syndrome(C-IRIS) in human immunodeficiency virus (HIV)- infected patients manifests as a clinical worsening or new presentation of cryptococcal disease after initiating anti-retroviral therapy (ART). This review will discuss the clinical features, immunopathogenesis and management of this syndrome.

Key words: Human immunodeficiency virus, Acquired immune deficiency syndrome, Cryptococcal, Immune reconstitution inflammatory syndrome

胡志亮, 许传军. 人类免疫缺陷病毒相关隐球菌免疫重建炎症综合征研究进展[J]. 新发传染病电子杂志, 2020, 5(2): 126-130.

Hu Zhiliang, Xu Chuanjun. Human immunodeficiency virus-associated cryptococcal immune reconstitution inflammatory syndrome[J]. Electronic Journal of Emerging Infectious Diseases, 2020, 5(2): 126-130.

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