2017—2019年深圳市寄生虫疑似病例血清学分析

doi:10.19871/j.cnki.xfcrbzz.2021.02.011

摘要/Abstract

摘要： 目的利用疾病预防控制检测平台检测寄生虫疑似病例血清抗体,分析深圳市门诊患者感染寄生虫的现状,为医院制订寄生虫感染防治策略提供科学依据。方法采用酶联免疫吸附检验方法,对深圳市市属、区属医院2017—2019年送检的2157份常见寄生虫感染疑似病例血样进行肝吸虫、蛔虫、肺吸虫、囊虫、广州管圆线虫、血吸虫、包虫、旋毛虫和裂头蚴虫等9种常见寄生虫病进行血清抗体检测,以描述性流行病学方法分析其感染特征。结果市属、区属医院2157份疑似病例血样9种寄生虫血清抗体总阳性率为26.38%（569/2157）,肝吸虫、蛔虫、肺吸虫、囊虫、广州管圆线虫、血吸虫、包虫、旋毛虫、裂头蚴虫的血清抗体阳性率依次为7.97%(155/1946)、8.78%(169/1924)、2.73%(56/2048)、7.19%(148/2058)、4.54%(93/2049)、2.47%(48/1943)、2.67%(55/2059)、2.18%(44/2022)、5.49%(113/2058),其中蛔虫、肝吸虫和囊虫3种寄生虫病感染率最为突出。市属、区属医院血清阳性率分别为23.18%（452/1950）、56.52%（117/207）,阳性率差异有统计学意义（P<0.05）;男性血清阳性率为27.49%（361/1313）,高于女性血清阳性率24.64%（208/844）,阳性率差异无统计学意义（P>0.05）;不同年龄组疑似病例血清样本阳性率存在差异,21~50岁年龄组血清阳性率[27.61%（346/1253）]高于0~20岁年龄组[11.19%(78/697)]和51岁以上年龄组[26.32%（145/551）],不同年龄组血清阳性率差异有统计学意义。结论深圳市门诊病例寄生虫感染率较高,其中淡水生物性食源性寄生虫病以肝吸虫为主,肠道寄生虫病以蛔虫为主,感染者多为21~50岁男性,应加强防治宣传和监测管理,进一步研究寄生虫病的区域分布特征,重点防治。

关键词: 寄生虫, 疑似病例, 抗体阳性率, 分析

Abstract: Objective To analyze the current situation of infected parasites in outpatients in Shenzhen by using the disease control detection platform to detect the serum antibodies of parasitic suspected cases, which provides a scientific basis for hospitals to formulate strategies for the prevention and control of parasitic infection. Methods Using the enzyme-linked immunosorbent assay (ELISA) to diagnose the common parasitic diseases of 2157 blood samples that sent by the municipal and district hospitals in 2017—2019, they were carried out the serum antibodies for 9 kinds of common parasitic diseases such as clonorchis sinensis, ascarid, paragonimiasis, cysticercus, angiostrongylus cantonensis, schistosomiasis, hydatid, trichinella spiralis, sparganum, and their infection characteristics were analyzed by descriptive epidemiological methods. Results The total positive rate of serum antibodies of 9 parasites in 1290 suspected cases from municipal and district hospitals was 26.38% (569/2157), the positive rates of serum antibodies of clonorchis sinensis, ascarid, paragonimiasis, cysticercus, angiostrongylus cantonensis, schistosomiasis, hydatid, trichinella spiralis, sparganum were 7.97%(155/1946)、8.78%(169/1924)、2.73%(56/2048)、7.19%(148/2058)、4.54%(93/2049)、2.47%(48/1943)、2.67%(55/2059)、2.18%(44/2022)、5.49%(113/2058) respectively, among which the ascarid, clonorchis sinensis and cysticercus have the highest infection rates. And the positive rates of blood samples in the municipal and district hospitals were 23.18%(452/1950) and 56.52%（117/207） respectively, the difference was statistically significant (P<0.05); otherwise ,the male seroprevalence rate was 27.49%（361/1313）, which was higher than the female seroprevalence rate of 24.64% (208/844), The difference was no statistically significant ( P>0.05); Moreover, different age groups in suspected cases showed different seroprevalence rates. The highest seroprevalence rate was distributed in the age group of 21-50 years (27.61%), higher than 0-20 years and older than 51 years old. There was significant difference in seroprevalence among them. Conclusions The parasitic infection rate of outpatients in Shenzhen is relatively high, in which clonorchiasis is the main form of freshwater food borne parasitic diseases, Ascaris is the main form of intestinal parasitic diseases, and most of them are men aged 21-50 years. Therefore, it is necessary to strengthen the prevention and control publicity and monitoring management, further study the regional distribution characteristics of parasitic diseases, and focus on prevention and control.

Key words: Parasitic, Suspected case, Antibody positive rate, Analyse

张泽娜, 叶燕芬, 唐屹君, 张志诚, 林晓仕. 2017—2019年深圳市寄生虫疑似病例血清学分析[J]. 新发传染病电子杂志, 2021, 6(2): 125-128.

Zhang Zena, Ye Yanfen, Tang Yijun, Zhang Zhicheng, Lin Xiaoshi. Serological analysis of suspected parasitic cases in Shenzhen from 2017 to 2019 years[J]. Electronic Journal of Emerging Infectious Diseases, 2021, 6(2): 125-128.

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