脊柱结核合并椎旁脓肿患者抗结核病灶持续冲洗治疗的临床分析

新发传染病电子杂志 ›› 2018, Vol. 3 ›› Issue (1): 41-44.

脊柱结核合并椎旁脓肿患者抗结核病灶持续冲洗治疗的临床分析

袁善有, 马克, 骆子义

深圳市第三人民医院外五科,广东深圳 518112

收稿日期:2017-11-16 出版日期:2018-02-28 发布日期:2020-06-29
通讯作者: 马克,Email：13602517196@qq.com
基金资助:
深圳市科技计划项目（JCY2015040211143616）

Continual irrigation of tuberculosis lesions in patients with spinal tuberculosis complicated by paravertebral abscess

YUAN Shan-you, MA Ke, LUO Zi-yi

Fifth Surgery Department, Third People's Hospital of Shenzhen, Guangdong Shenzhen 518112,China

Received:2017-11-16 Online:2018-02-28 Published:2020-06-29

摘要/Abstract

摘要： 目的研究给予脊柱结核合并椎旁脓肿患者抗结核病灶持续冲洗的治疗效果。方法选择2013年9月至2017年11月我院接诊的60例脊柱结核合并椎旁脓肿的患者进行研究,按照随机数表法将所有患者均分为研究组和对照组。研究组30例患者给予病灶持续冲洗方法进行治疗,对照组30例患者给予常规引流法进行治疗。对两组患者的术后7天内平均体温,术后并发症发生情况,两组患者术前、术后血沉降率情况进行比较。结果研究组患者的术后7天内的体温波动呈现逐渐降低的趋势,对照组患者术后7天内的体温呈现上下波动的趋势,研究组患者的体温均低于对照组的组间体温,差异有统计学意义（P<0.05）;两组的组间、不同时间点的差异比较无统计学意义（P>0.05）。手术前两组患者的血沉情况差异无统计学意义（P>0.05）;术后第20天,两组患者的血沉降率与手术前比较有显著降低,差异有统计学意义（P<0.01）。术后第20天,两组间血沉降率差异无统计学意义（P>0.05）。研究组（3.33%）患者的并发症发生率显著低于对照组（26.67%）,差异具有统计学意义（P<0.05）。结论给予脊柱结核合并椎旁脓肿患者抗结核病灶持续冲洗治疗,能够有效降低患者术后7天内的体温以及术后并发症发生率,值得临床推广应用。

关键词: 脊柱结核, 椎旁脓肿, 病灶, 持续冲洗, 疗效

Abstract: Objective To assess the therapeutic efficacy of continual irrigation of tuberculosis lesions in patients with spinal tuberculosis complicated by paravertebral abscess. Methods A total of 60 patients with spinal tuberculosis complicated by paravertebral abscess had been admitted to our hospital from September 2013 to November 2017. All the patients were randomly divided into a study group and a control group. The 30 patients in the study group were treated with continual irrigation of lesions, while the 30 patients in the control group received conventional drainage for treatment. The two groups of patients were compared in terms of mean body temperature within 7 days after the operation, postoperative complications as well as pre- and post-operative erythrocyte sedimentation rate (ESR) . Results The body temperature of the study group decreased gradually within 7 days after the operation, while the body temperature of the control group showed fluctuation within 7 days after the operation. The body temperature of the study group was lower than that of the control group, and the difference was statistically significant (P<0.05). The body temperature showed no significant difference between the two groups at different time points (P>0.05). The pre-operative ESR showed no significant difference between the two groups (P>0.05). At post-operative d 20, the ESR of both groups decreased significantly, compared with that before the operation (P<0.01), while the difference between the two groups showed no statistical significance (P>0.05). The incidence of postoperative complications in the study group was significantly lower than that in the control group (3.33% vs 26.67%, P<0.05). Conclusion Continual irrigation of tuberculosis lesions in patients with spinal tuberculosis complicated by paravertebral abscess can effectively reduce the body temperature of patients within 7 days after operation and the incidence of postoperative complications, which should be promoted for wider clinical application.

Key words: Spinal tuberculosis, Paravertebral abscess, Lesion, Continual irrigation, Therapeutic efficacy

袁善有, 马克, 骆子义. 脊柱结核合并椎旁脓肿患者抗结核病灶持续冲洗治疗的临床分析[J]. 新发传染病电子杂志, 2018, 3(1): 41-44.

YUAN Shan-you, MA Ke, LUO Zi-yi. Continual irrigation of tuberculosis lesions in patients with spinal tuberculosis complicated by paravertebral abscess[J]. Electronic Journal of Emerging Infectious Diseases, 2018, 3(1): 41-44.

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