人民卫生出版社系列期刊
ISSN 2096-2738 CN 11-9370/R

中国科技核心期刊(中国科技论文统计源期刊)
2020《中国学术期刊影响因子年报》统计源期刊

新发传染病电子杂志 ›› 2022, Vol. 7 ›› Issue (3): 90-94.doi: 10.19871/j.cnki.xfcrbzz.2022.03.019

• 教育园地 • 上一篇    

肠结核的临床影像诊断及与克罗恩病的鉴别诊断

郑广平1, 罗杰棋1, 鲍晓慧1, 陆普选2, 魏方军1   

  1. 1. 深圳市第三人民医院放射科,广东 深圳 518112;
    2. 深圳市慢性病防治中心影像科,广东 深圳 518020
  • 收稿日期:2022-05-22 出版日期:2022-07-31 发布日期:2022-09-08
  • 通讯作者: 魏方军,Email:666333624@qq.com
  • 基金资助:
    深圳市基础研究专项(面上项目)(JCYJ20190813153413160)

Clinical imaging diagnosis of intestinal tuberculosis and the differential diagnosis with Crohn disease

Zheng Guangping1, Luo Jieqi1, Bao Xiaohui1, Lu Puxuan2, Wei Fangjun1   

  1. 1. Department of Radiology, Shenzhen Third People's Hospital, Guangdong Shenzhen 518112, China;
    2. Department of Radiology, Shenzhen Center for Chronic Disease Control, Guangdong Shenzhen 518110, China
  • Received:2022-05-22 Online:2022-07-31 Published:2022-09-08

摘要: 结核病在全世界仍处在一个较高发病区间,是全世界的重大公共卫生问题。中国是占全球结核病总数2/3的8个国家中的一员,结核病防控形势依然严峻。肠结核多继发于肺结核,是腹部结核中最常见的一种,肠结核85%~90%位于回盲部,即位于回盲瓣及其相邻的回肠和结肠,其他发病部位依次为升结肠、空肠、横结肠等。肠结核一般起病缓慢,可表现为腹痛、腹部包块、腹泻与便秘等。影像学检查对肠结核诊断具有重要意义,尤其是腹部CT检查对了解肠道病变的内部结构、肠壁的浸润程度等均有较大价值;X线气钡双对比造影、PET/CT检查有一定的诊断意义,但临床上较少应用。腹部CT平扫,肠结核多表现为肠壁环形增厚、肠腔狭窄,可呈肠道跳跃性改变;CT增强扫描见病变段肠壁明显呈均匀强化,且有分层现象,表现为“靶征”和“双环征”。克罗恩病是一种原因不明的肠道炎症性疾病,亦好发于回肠及右半结肠,病变呈节段性、跳跃性改变。影像学和纤维肠镜检查发现,克罗恩病与肠结核两者黏膜溃疡不同,克罗恩病为多发纵横交错的线形溃疡,以纵行溃疡为特点,肠结核则以横行的、全周性的带状溃疡和星状溃疡为特点。克罗恩病与肠结核鉴别困难时需依靠病理检查,克罗恩病组织病理观察无干酪样病变,而肠结核可出现干酪样病变。

关键词: 肺结核, 肠结核, 克罗恩病, 影像学诊断, 鉴别诊断

Abstract: Tuberculosis (TB) still has a relatively high incidence in the world, and it is a sever public health problem. China is one of eight countries that account for two-thirds of the global TB total, and the prevention and control of TB remains grim. Intestinal tuberculosis, secondary to tuberculosis, is the most common type of abdominal tuberculosis. About 85%-90% of intestinal tuberculosis is located in the ileocecal valve and its adjacent ileum and colon, and the other parts are ascending colon, jejunum, transverse colon, etc. Bowel tuberculosis has the disease slowly commonly, and can manifest abdominal pain, abdominal wrap, diarrhea and constipation. Imaging examination is of great value in the diagnosis of intestinal tuberculosis. In particular,abdominal CT scan have a important role in understanding the internal structure of intestinal lesions and the degree of intestinal wall infiltration. In addition, colon double contrast imaging and PET/CT examination has certain diagnostic ability, but it is rarely used in clinic.Plain CT scan of the abdomen showed that intestinal tuberculosis usually manifest annular thickening of the intestinal wall and narrowing of the intestinal lumen, which may show intestinal skipping changes. Contrasted CT scan showed obvious uniform enhancement of the intestinal wall of the lesion area, and stratified phenomenon, “target sign” and“double ring sign”. Crohn disease is an inflammatory disease of intestinal tract of unknown cause, and also occurs in ileum and right colon with segmental and skipping lesions. Imaging and fiber-colonscopy revealed that Crohn disease and intestinal tuberculosis were different from mucosal ulcers. Crohn disease was multiple linear ulcers crisscrossing and characterized by longitudinal ulcers, while intestinal tuberculosis was characterized by transverse, circumferent banded ulcers and stellate ulcers. It is difficult to distinguish Crohn disease from intestinal tuberculosis by pathological examination. No caseous lesions were observed in Crohn disease histopathology, while caseous lesions may occur in intestinal tuberculosis.

Key words: Pulmonary tuberculosis, Intestinal tuberculosis, Crohn disease, Imaging diagnosis, Differential diagnosis