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新发传染病电子杂志 ›› 2023, Vol. 8 ›› Issue (3): 84-89.doi: 10.19871/j.cnki.xfcrbzz.2023.03.018

• 综述 • 上一篇    下一篇

肠道病毒感染相关疾病的流行特征研究进展

邱方洲, 沈永明   

  1. 天津市儿童医院检验科,天津 300074
  • 收稿日期:2022-09-13 出版日期:2023-06-30 发布日期:2023-07-20
  • 通讯作者: 沈永明,shenymtj@sina.com

Progress in studying the epidemic characteristics of diseases associated with human enterovirus

Qiu Fangzhou, Shen Yongming   

  1. Department of Laboratory Medical, Tianjin Children's Hospital, Tianjin 300074, China
  • Received:2022-09-13 Online:2023-06-30 Published:2023-07-20

摘要: 人肠道病毒(HEV)能感染人类,引起世界范围的暴发流行,同时可诱发多种临床症状,主要包括发热、头痛、呼吸道感染疾病、咽痛,偶尔还有呕吐和腹泻等症状。有些特定血清型HEV能够引发严重疾病,但大部分HEV感染症状轻微甚至无症状。本文综述了已报道的部分与HEV感染相关疾病包括手足口病、急性弛缓性瘫痪、脑炎脑膜炎、糖尿病、腹泻、呼吸系统疾病、急性出血性结膜炎、急性中耳炎的流行特征研究进展;并进一步总结HEV在不同感染性疾病中的分子流行特征、致病机制进展,阐述HEV与人类感染性疾病的关系。

关键词: 人肠道病毒, 感染性疾病, 流行特征

Abstract: Human enterovirus (HEV) can infect people and outbreak all over the world. At the same time, it can induce a variety of clinical symptoms, including fever, headache, respiratory tract infection, sore throat, and occasionally vomiting and diarrhea. Some specific serotypes can cause serious diseases, but most of the HEV infection symptoms are mild or even asymptomatic. In this review, we will summarize the research progress and current situation of reported diseases related to HEV infection (including hand foot mouth disease, acute flaccid paralysis, encephalitis/meningitis, diabetes, diarrhea, respiratory diseases, acute hemorrhagic conjunctivitis and acute otitis media. Further summarize the molecular epidemic characteristics and pathogenesis of HEV in different infectious diseases, and elaborate the relationship between HEV and human infectious diseases.

Key words: Human enterovirus, Infectious diseases, Epidemic characteristic

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