关键词: 临床药师, 结核性脑膜炎, 化脓性脑膜炎, 药物相互作用, 不良反应, 婴儿

Abstract: This article reviews on the proactive intervention and monitoring of a scientific pharmacist in the administration of an child with tuberculous meningitis blended with purulent meningitis. The patient, a 6-month and 3-day-old child, was diagnosed with tuberculous meningitis, purulent meningitis, and secondary epilepsy. The clinical pharmacist notified the clinic about the potential drug interactions between meropenem and sodium valproate, which could worsen the seizures. After consulting with the healthcare team, the child's convulsions were gradually controlled. The frequency of linezolid was adjusted from every 8 hours to every 12 hours. After adjusting the frequency of linezolid for three days, the child exhibited the ability to track light and objects with both eyes. Following this improvement, the child was discharged and scheduled for regular check-ups. The anti-tuberculosis regimen was continued for nearly 10 months with adjusted frequency of linezolid, and no further adverse drug reactions were reported.

Key words: Clinical pharmacist, Tuberculous meningitis, Purulent meningitis, Drug interactions, Adverse reactions, Infant