结核空洞性病变CT特征及治疗后转归征象

新发传染病电子杂志 ›› 2018, Vol. 3 ›› Issue (3): 178-181.

结核空洞性病变CT特征及治疗后转归征象

彭程¹, 王立非¹, 梁芳芳², 曹毅¹, 陈晓芳¹, 郑广平¹

1.深圳市第三人民医院放射科,广东深圳 518020;
2.深圳市儿童医院血液科,广东深圳 218012

收稿日期:2018-06-18 出版日期:2018-08-31 发布日期:2020-06-30
通讯作者: 梁芳芳,Email：liangfangfang@163.com
基金资助:
中山大学肿瘤防治中心张福君教授重症肝病影像诊断与微创介入治疗团队基金支持（SZSM201612053）

CT demonstrations of cavitary pulmonary tuberculosis before and after antituberculotic treatment: A comparative study for signs of convertion

PENG Cheng¹, WANG Li-fei¹, LANG Fang-fang², CAO Yi¹, CHEN Xiao-fang¹, ZHENG Guang-ping¹

1. Department of Radiology Diseases, Shenzhen Third people's hospital, Guangdong Shenzhen 518020, China;
2. Shenzhen Children's Hospital, Guangdong Shenzhen 518020, China

Received:2018-06-18 Online:2018-08-31 Published:2020-06-30

摘要/Abstract

摘要： 目的通过分析肺结核的CT征象,探讨活动性肺结核空洞病变与治疗后残留空洞的鉴别诊断。方法收集2009年10月至2017年10月进行登记治疗初治涂片阳性肺结核的患者资料,观察患者在接受治疗前以及接受治疗后与随访过程中,患者肺结核空洞性病变的CT征象变化趋势,分析空洞及空洞周围的的不同影像征象,采用单变量和多变量logistic回归分析比较治疗前后空洞CT征象,以治疗后残留空洞作为对照组计算优势比。结果单变量分析空洞直径（P<0.05）、卫星灶（P<0.05）、和相邻支气管扩张（P<0.001）与活动性空洞有显著统计学关联性,毛刺/条索与治疗后残留空洞有显著的统计学关联性（P<0.001）。多变量分析空洞直径（P<0.05）和支气管扩张（P<0.05）与活动性空洞有显著的统计学关联性,毛刺/条索与治疗后残留空洞有显著的统计学关联性（P<0.05）。结论空洞性病变治疗后所形成的毛刺/条索征是鉴别空洞与否活动的重要因素。

关键词: 空洞/肺结核, CT

Abstract: Objective To investigate and compare the HRCT demonstrations of cavitary pulmonary tuberculosis before and after treatment for signs of converstion. Methods A total of 48 cases of cavitary pulmonary tuberculosis were collected. And all of the patients received at least two CT scans before and after antituberculotic treatment. The differences of CT scan demonstrations of and around the cavitary lesions were analyzed, and the evolvement of cavitary lesions were observed comparatively. Univariate and multivariate logistic regression analysis were performed for statistical differences before and after treatment. The residual ratio of residual cavitary lesion after treatment was selected as the control to calculate the odds ratio. Results Univariate analysis of the diameter of cavitary lesion (P<0.05), satellite foci (P<0.05), and adjacent bronchiectasis (P<0.001) were significantly associated with active cavitary lesions. The spikes and cords like demonstrations were significantly associated with residual cavitary lesions after treatment (P<0.001). Multivariate analysis revealed that the diameter of cavitary lesion and bronchiectasis were significantly correlated with active cavitary lesion (P<0.05). And the spike and cords like demonstrations were significantly associated with the residual cavitary lesion after treatment (P<0.05). Conclusion The spike and cords like demonstrations formed after anti-tuberculotic treatment are signs signaling the activation of cavitary lesions.

Key words: Cavitary/Pulmonary uberculosis, CT

彭程, 王立非, 梁芳芳, 曹毅, 陈晓芳, 郑广平. 结核空洞性病变CT特征及治疗后转归征象[J]. 新发传染病电子杂志, 2018, 3(3): 178-181.

PENG Cheng, WANG Li-fei, LANG Fang-fang, CAO Yi, CHEN Xiao-fang, ZHENG Guang-ping. CT demonstrations of cavitary pulmonary tuberculosis before and after antituberculotic treatment: A comparative study for signs of convertion[J]. Electronic Journal of Emerging Infectious Diseases, 2018, 3(3): 178-181.

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