寨卡病毒感染神经系统损伤及影像学表现

新发传染病电子杂志 ›› 2016, Vol. 1 ›› Issue (1): 14-17.

寨卡病毒感染神经系统损伤及影像学表现

高波¹, 曾瑜²

1.烟台毓璜顶医院影像科,山东烟台 264000;
2.贵州医科大学附属医院放射科,贵州 550004

收稿日期:2016-10-23 出版日期:2016-11-30 发布日期:2020-07-01
通讯作者: 高波,Email：gygb2004@163.com
基金资助:
国家自然科学基金面上项目（81471645）; 山东省重点研发计划项目（2015GSF118185）; 山东省自然科学基金（ZR2014HL084）

Nervous system injury and neuroimaging finding of Zika virus infection

GAO Bo¹, ZENG Yu²

1. Yantai Yuhuangding hospital,Shandong Yantai 264052,China;
2. Department of Radiology,Affiliated Hospital of Guizhou Medical University,Guizhou 550004,China

Received:2016-10-23 Online:2016-11-30 Published:2020-07-01

摘要/Abstract

摘要： 近几年,Zika病毒在全球发生了大规模传播。2016年,世界卫生组织将其列为全球紧急公共卫生事件。Zika病毒感染对神经系统损伤是对人类健康的主要威胁,主要包括小头畸形及格林-巴利综合征。前者影像学上最常见的是皮质和皮质下白质的交界处钙化,此外包括白质萎缩、巨脑室伴或不伴脑积水、皮质畸形、脑组织钙化、小脑及脑干萎缩、小脑延髓池扩大等;后者影像表现主要为冠状位T1WI增强增强扫显示神经组织强化。本文主要就Zika病毒感染神经系统损伤及其影像学表现作一综述,以提高对本病的认识和防治水平。

关键词: Zika病毒, 神经系统损伤, 小头畸形, 格林-巴利综合征, 影像学

Abstract: Recently,Zika virus disease is prevalent in the global.WHO declared that Zika virus was of global public health importance in 2016.The major threat to human health is that Zika virus infection leads to nervous system injury,including microcephaly and Guillain-Barre syndrome.The neuroimaging finding of the microcephaly with Zika virus infection most commonly include brain calcifications in the junction between cortical and subcortical white matter associated with abnormalities of cortical.Additional findings include diminution of white matter,large ventricles with or without hydrocephalus,cortical malformations,brain calcification,hypoplasia of the cerebellum and the brainstem,cerebellomedullary cistern enlargement and so on;the Guillain-Barre syndrome is mainly contrast enhancement of the nerve.This review describes the nervous system injury and imaging findings of Zika virus infection,in order to improve the imaging understanding and control of this disease.

Key words: Zika virus, Nervous system injury, Microcephaly, Guillain-Barré syndrome, Imaging

高波, 曾瑜. 寨卡病毒感染神经系统损伤及影像学表现[J]. 新发传染病电子杂志, 2016, 1(1): 14-17.

GAO Bo, ZENG Yu. Nervous system injury and neuroimaging finding of Zika virus infection[J]. Electronic Journal of Emerging Infectious Diseases, 2016, 1(1): 14-17.

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