Abstract: Objective To investigate the characteristic CT images of IgG4-related sialadenitis. Methods The clinical and imaging data of 10 patients with IgG4- related sialadenitis confirmed by pathologic examination were retrospectively analyzed. In the 10 cases, 8 patients were performed with enhanced scan, and the imaging features such as lesion size, morphology, distribution, CT value and enhancement pattern were analyzed. Results All patients showed salivary gland diffuse or multi nodulated enlargement, including 4 cases of unilateral parotid involvement, 5 cases of unilateral submandibular gland involvement, 1 case of bilateral submandibular gland simultaneously, while 5 cases showed with submandibular lymph nodes increased, and 3 cases showed with cystic changes. CT scan showed lacking structured morphology of unilateral or bilateral salivary gland, presenting in multiple nodular, lightly lobulated or diffuse enlarged. Uneven enhancement was observed in the salivary glands during the arterial phase. And nodules were significantly enhanced, the unequal thickness low-density zone was formed between nodules, and little proliferation can be detected in the surrounding accompanying with increased small lymph nodes. Conclusion IgG4-related sialadenitis has specific characteristic CT features. Accurate knowledge of these signs facilitates to improve the preoperative diagnosis rate of IgG4-related sialadenitis.

Key words: IgG4-related sialadenitis, CT diagnosis, Pathology