Abstract: Objective To discuss the thoracic and abdominal CT manifestations and the diagnostic value for AIDS patients complicated with penicillium marneffei infection. Methods Totally 16 AIDS patients complicated with penicillium marneffei infection were retrospectively analyzed for their thoracic CT findings, while 9 cases for abdominal CT findings. Results Regarding to the thoracic CT findings, 5 cases were showed with lateral (1 case) or bi-lateral (4 cases) patchy consolidations of lung tissue (31.25%); 5 cases with pulmonary nodules including 2 cases of miliary shadow (31.25%); 4 cases with single (3 cases) or clustering (1 case) cavities(25%); 4 cases with bi-lateral ground-glass opacity(25.00%); 3 cases were found with pulmonary portal and mediastinal lymphadenopathy(18.87%); 2 cases with hydrothorax(12.50%); 1 case with pulmonary mass(6.25%); 1 case with hydropericardium(6.25%); and 1 case with axillary lymphadenopathy(6.25%). As for abdominal CT findings, 5 cases were found with retroperitoneal and mesenteric lymphadenopathy(55.56%); 4 cases with hepatic low-density(44.44%), including 3 cases of focal distributions and 1 cases of diffuse distribution; 4 cases with hepatomegaly(44.44%); 2 cases with spleen low-density(22.22%); 2 cases with ascites(22.22%); 1 case with intestinal wall thickening(11.11%); and 1 case with splenomegaly(11.11%). Conclusion Thoracic and abdominal CT findings of AIDS patients complicated with penicillium marneffei infection are various and complex. The thoracic CT findings are primary patchy consolidations of lung tissue, pulmonary nodules, cavities, ground-glass opacity, and pulmonary portal and mediastinal lymphadenopathy. The abdominal CT findings are primary retroperitoneal and mesenteric lymphadenopathy, hepatic low-density, hepatomegaly, spleen low-density, and splenomegaly. Multiple and complicated findings can be observed in single paitent.

Key words: Acquired immunodefieiency syndrome, Penicillium Marneffe, Tomography, X-ray computed