Image analysis of multiple organ invasion in acquired immunodeficiency syndrome patients with Kaposi's sarcoma

Electronic Journal of Emerging Infectious Diseases ›› 2020, Vol. 5 ›› Issue (1): 8-15.

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Image analysis of multiple organ invasion in acquired immunodeficiency syndrome patients with Kaposi's sarcoma

Lu Yibo¹, Shi Yuxin², Liu Jinxin³, Zhang Qianqian^4,5, Xie Ruming⁶, Lu Zhiyan⁷, Yang Yuxin⁸, Zhang Na⁸, Zheng Guangping⁴, Ye Wen², Chen Budong⁶, Wu Fengyao¹, Li Hongjun¹⁰, Lu Puxuan^4,11

1.Department of Critical Medicine, The Fourth People's Hospital of Nanning, Nanning 530023,China;
2.Department of Radiology, Shanghai Public Health Clinical Center, Shanghai 201805,China;
3.Department of Radiology, The Eighth People's Hospital of Guangzhou, Guangzhou 510060,China;
4.Department of Radiology, The Third People's Hospital of Shenzhen, Guangdong Shenzhen 518112, China;
5.Department of Radiology, Henan Zhoukou central hospital, Henan Zhoukou 466000, China;
6.Department of Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China;
7.Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan 430017, China;
8.Department of Radiology, The Sixth People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830000, China;;
9.Department of Radiology, Chengdu Public Health Clinical Center, Chengdu 610000, China;
10.Department of Radiology, Beijing You’an Hospital, Capital Medical University, Beijing 100069, China;;
11.Department of Radiology, Shenzhen Center for Chronic Disease Control,Guangdong Shenzhen 518020, China

Online:2020-01-20 Published:2020-04-22

Abstract

Abstract: Objective To analyze the clinical imaging manifestations of multiple organ tissue invasion of AIDS with Kaposi's sarcoma, to improve the understanding of AIDS with kaposi's sarcoma, and provide the basis for clinical diagnosis and treatments. Methods Relevant datas of AIDS complicated with Kaposi's sarcoma diagnosed in several infectious hospitals in China were collected. According to the inclusion and exclusion criteria, clinical manifestations, imaging and pathological data of 48 patients meeting the requirements were sorted and analyzed. Results In 48 patients with AIDS with Kaposi's sarcoma, CD4⁺ T cell count was lower than 100 /UL in 37 patients (77.1%). 38 patients suffered from lung invasion, and 30 patients (30/38,78.9%) presented nodular shadows on the images. CT transversely located pulmonary window and mediastinal window, as well as coronal pseudocolor reconstruction, showed nodules with different lung sizes and vascular distribution. which were characterized by nodules of both lungs widely connected with pulmonary vessels, or flame-like/star-like, fruit hanging signs. Kaposi's sarcoma of the liver showed nodules and intrahepatic bile duct dilatation in 7 cases. 3 patients with AIDS complicated with Kaposi's sarcoma suffered from esophageal, gastric and intestinal invasion. 1 case with thyroid invasion showed low-density nodules. 1 case of rib invasion and 1 case of maxillary invasion were lytic destruction and surrounding soft tissue nodules. Two or more organs and organizers were involved in 44 cases. Conclusion The main imaging manifestations of multiple organs of AIDS with Kaposi's sarcoma are pleomorphic and vascular nodules. AIDS complicated with kaposi's sarcoma is accompanied by invasion of lung, liver, digestive tract, thyroid, rib and maxilla, and their imaging manifestations are mainly irregular nodules closely related to blood vessels.

Key words: Acquired immunodeficiency syndrome, Kaposi's sarcoma, Viscera/Tissues, Computed tomography, Magnetic resonance imaging

Lu Yibo, Shi Yuxin, Liu Jinxin, Zhang Qianqian, Xie Ruming, Lu Zhiyan, Yang Yuxin, Zhang Na, Zheng Guangping, Ye Wen, Chen Budong, Wu Fengyao, Li Hongjun, Lu Puxuan. Image analysis of multiple organ invasion in acquired immunodeficiency syndrome patients with Kaposi's sarcoma[J]. Electronic Journal of Emerging Infectious Diseases, 2020, 5(1): 8-15.

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Image analysis of multiple organ invasion in acquired immunodeficiency syndrome patients with Kaposi's sarcoma

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