People's Health Press
ISSN 2096-2738 CN 11-9370/R
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Electronic Journal of Emerging Infectious Diseases ›› 2021, Vol. 6 ›› Issue (2): 160-162.doi: 10.19871/j.cnki.xfcrbzz.2021.02.019

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Pharmacodynamic characteristics of non-depolarizing muscle relaxants in patients with tuberculosis

Liu Minqiang1, Hong Fengzhu2, Shi Haowen1, Tang Yimin2, Li Zhichao1, He Renliang1   

  1. 1. Department of Anesthesiology, the Third People's Hospital of Shenzhen, Guangdong Shenzhen 518112, China;
    2. Department of Pulmonary Clinic, the Third People's Hospital of Shenzhen, Guangdong Shenzhen 518112, China
  • Received:2020-12-26 Online:2021-05-31 Published:2021-06-24

Abstract: Non-depolarizing muscle relaxants (NDMR) are the most widely used skeletal muscle relaxants in clinical practice. The pharmacodynamic characteristics of NDMR are related to many factors. Tuberculosis (TB) patients would cause liver dysfunction and neuro-muscular system damage due to their pathophysiological characteristics and long-term medication treatment, which affects the blocking time of NDMR. To understand the characteristics of tuberculosis on the pharmacology of NDMR is of great significance for individualized medication in perioperative period.

Key words: Tuberculosis, Non-depolarizing muscle relaxants, Pharmacodynamics