Abstract: Objective To Analyze the related indications for prevention of mother-to-child transmission of AIDS, syphilis and viral hepatitis B in Qingdao from 2017 to 2021,so as to provide ideas and basis for promoting the elimination of mother-to-child transmission. Method The date of national information system for the prevention of mother-to-child transmission of HIV,syphilis and HBV was used to analyze the related indications and their annual changes. Result From 2017 to 2021, the number of maternity in Qingdao was 513 066. All the detection rates of HIV,syphilis and HBV were 100%. The positive detection rates of HIV and syphilis were 0.58/10 000, 0.27%,respectively, and showed an increasing trend（P<0.05）; the positive detection rate of HBV was 3.54%, and showed a decreasing trend(P<0.001). During the 5 years, the treatment rates of both HIV positive pregnant women and infants born to pregnant women with HIV increased, which were 100% in the nearly three years; the treatment rate of pregnant women with syphilis increased from 64.6%(2017) to 97.53%(2021) and that of infants born to pregnant women with syphilis increased from 50.16%(2017) to 95.53%(2021) year by year, both with statistically significance(P<0.001). The inoculation rate of immune globulin for infants born to pregnant women with HBV was 99.98%. From 2017 to 2021,the rate of mother-to-child transmission of HIV was 0;the incidence rate of congenital syphilis was 0.39/100 000; the HBsAg positive rate of children younger than 12 months born to pregnant women with HBV was 0.8% in 2021. Conclusion From 2017 to 2021, The indications for prevention of mother-to-child transmission of HIV,syphilis and HBV were all improved in Qingdao and the mother-to-child transmission rates remained at a low level. But the treatment rates of pregnant women with HIV and syphilis are still needed to consolidate. Preparing for elimination of mother-to-child transmission, further intervention measures must be strengthened in the future work.

Key words: Human immunodeficiency virus, Acquired immune deficiency syndrome, Syphilis, Hepatitis B virus, Viral hepatitis B, Mother-to-child transmission, Pregnant women