Abstract: Tuberculosis is the second largest killer of infectious diseases after coronavirus disease 2019(COVID-19), and it also is the 13^th largest cause of death in the world. The global tuberculosis(TB) report 2022 shows that, an estimated 10.6 million people worldwide will be infected with tuberculosis in 2021, of which 6 million will be men, 3.4 million women and 1.2 million children. HIV-positive people accounted for 6.7 percent of the total. The reported number of people newly diagnosed with TB had recovered from 5.8 million in 2020 to 6.4 million in 2021, but there were still about 4.2 million people who had not been diagnosed or reported. The incidence rate of tuberculosis had risen with an increased number of TB deaths. In 2021, the estimated number of deaths caused by TB was more than double the number caused by HIV/AIDS. 450 000 patients have been newly diagnosed with rifampicin-resistant tuberculosis (RR-TB) in 2021, which number was significantly higher than that in 2020. However, the treatment coverage and treatment success rate for drug-resistant tuberculosis(DR-TB) was still low. The report suggests that the impact of the COVID-19 epidemic on global tuberculosis prevention and control still continued. The report calls on multiple departments to redouble their efforts to increase funding for basic tuberculosis services and research, to reduce and reverse the negative impact of COVID-19 on tuberculosis prevention and control services, so as to achieve the goal of ending tuberculosis and save lives.

Key words: World Health Organization, Tuberculosis, Report, Coronavirus disease 2019, Acquired immunodeficiency syndrome