Abstract: AIDS associated lymphoma (ARL)is the most common malignant tumor in AIDS patients. Chemotherapy is the most effective treatment for ARL. Peripherally inserted central catheter(PICC) can effectively avoid the stimulation of chemotherapy drugs to the vein.However, a series of complications may occur during catheter indwelling. The incidence of catheter-related lymphatic leakage was less,Difficult to identify clinically. If not found and treated early, it may lead to unplanned extubation or catheter-related bloodstream infection and other serious consequences.This paper reports the identification and treatment of a case of catheter-related lymphatic leakage: through the patient's symptoms, signs, local examination of the catheter, combined with secretion microbial culture and ultrasonic exploration, the common factors such as local infection, catheter damage, fibrin sheath formation and so on were quickly eliminated, and finally it was determined as lymphatic leakage; The puncture point is covered with alginate dressing and gauze, and then according to the anatomical structure of the lymphatic vessels running along the basilic vein, the gauze is wrapped into a cylinder to compress the part, so that the stress point is concentrated, and then the adhesive elastic bandage is used to compress and wrap, and the local seepage can be quickly relieved through the above treatment. The catheter was retained for 4 months and the whole chemotherapy was completed. This case provides reference for clinical diagnosis, treatment and nursing.

Key words: Acquired immune deficiency syndrome related lymphoma, Peripherally inserted central catheter, Lymphatic leakage, Identification and disposal