Research progress of Zika virus

Abstract

Abstract: The most serious outbreak of Zika virus in history have been reported in South America from 2015 to 2016.During the epidemic,a significant increase of neonatal microcephaly and Guillain-Barré syndrome patients triggered a global concern.Zika virus belongs to the family Flaviviridae,genus Flavivirus.The epidemic viruses in South America were Asia subtype strains.The primary transmission route of Zika virus is via the Aedes mosquito.However,mounting evidence has shown that sexual transmission of Zika virus is more common than previously assumed.Zika virus disease usually has no symptoms or mild symptoms.But Zika virus in pregnant woman can infect the fetal nervous system,which could result in brain malformation.Nucleic acid detection is the primary method to detect the virus in laboratory.It has been detected in the blood,urine,semen,saliva and other body fluids by the method. There is no vaccine available till now and the current most effective way to prevent Zika virus infection is still prevention of mosquito bites.Pregnant women and couples planning a pregnancy must strengthen the personal protection,to avoid serious consequences of Zika virus infection.

Key words: Zika virus, Microcephaly, Guillain-Barré syndrome, Sexual transmission

WU Chun-li, YANG Fan, ZHANG Ren-li. Research progress of Zika virus[J]. Electronic Journal of Emerging Infectious Diseases, 2016, 1(1): 10-13.

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