Abstract: Recently,Zika virus disease is prevalent in the global.WHO declared that Zika virus was of global public health importance in 2016.The major threat to human health is that Zika virus infection leads to nervous system injury,including microcephaly and Guillain-Barre syndrome.The neuroimaging finding of the microcephaly with Zika virus infection most commonly include brain calcifications in the junction between cortical and subcortical white matter associated with abnormalities of cortical.Additional findings include diminution of white matter,large ventricles with or without hydrocephalus,cortical malformations,brain calcification,hypoplasia of the cerebellum and the brainstem,cerebellomedullary cistern enlargement and so on;the Guillain-Barre syndrome is mainly contrast enhancement of the nerve.This review describes the nervous system injury and imaging findings of Zika virus infection,in order to improve the imaging understanding and control of this disease.

Key words: Zika virus, Nervous system injury, Microcephaly, Guillain-Barré syndrome, Imaging